{"id":954,"date":"2026-07-29T11:52:00","date_gmt":"2026-07-29T02:52:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-29-personalized-lung-cancer-dna-vaccine-vi\/"},"modified":"2026-07-29T13:52:57","modified_gmt":"2026-07-29T04:52:57","slug":"2026-07-29-personalized-lung-cancer-dna-vaccine-vi","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-29-personalized-lung-cancer-dna-vaccine-vi\/","title":{"rendered":"Vaccine t\u1ea1o t\u1eeb \u201cb\u1ea3n thi\u1ebft k\u1ebf\u201d ung th\u01b0 \u0111\u1ebfn v\u1edbi b\u1ec7nh nh\u00e2n Anh \u0111\u1ea7u ti\u00ean"},"content":{"rendered":"

2026-07-29 11:52 KST<\/strong><\/p>\n

NEOVACC, vaccine DNA thi\u1ebft k\u1ebf t\u1eeb \u0111\u1ed9t bi\u1ebfn ri\u00eang c\u1ee7a kh\u1ed1i u m\u1ed9t b\u1ec7nh nh\u00e2n, \u0111\u00e3 \u0111\u01b0\u1ee3c d\u00f9ng cho b\u1ec7nh nh\u00e2n \u0111\u1ea7u ti\u00ean t\u1ea1i Anh.<\/p>\n

\u0110\u00e2y l\u00e0 th\u1eed nghi\u1ec7m \u0111\u1ea7u ti\u00ean \u1edf ng\u01b0\u1eddi trong nh\u00f3m ung th\u01b0 ph\u1ed5i r\u1ea5t ch\u1ecdn l\u1ecdc, nh\u1eb1m \u0111\u00e1nh gi\u00e1 an to\u00e0n v\u00e0 \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch, ch\u01b0a ch\u1ee9ng minh \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3.<\/p>\n

V\u00ec sao m\u1ed7i vaccine kh\u00e1c nhau<\/h2>\n

DNA t\u1eeb sinh thi\u1ebft kh\u1ed1i u \u0111\u01b0\u1ee3c so v\u1edbi t\u1ebf b\u00e0o b\u00ecnh th\u01b0\u1eddng, r\u1ed3i m\u00e1y t\u00ednh ch\u1ecdn bi\u1ebfn \u0111\u1ed5i m\u00e0 mi\u1ec5n d\u1ecbch c\u00f3 th\u1ec3 nh\u1eadn ra. C\u00e1c m\u1ee5c ti\u00eau \u0111\u00f3 t\u1ea1o thi\u1ebft k\u1ebf ri\u00eang.<\/p>\n

Hai ng\u01b0\u1eddi c\u00f9ng ch\u1ea9n \u0111o\u00e1n v\u1eabn c\u00f3 \u0111\u1ed9t bi\u1ebfn kh\u00e1c nhau; \u0111\u00e2y kh\u00f4ng ph\u1ea3i vaccine ph\u00f2ng b\u1ec7nh gi\u1ed1ng nhau cho m\u1ecdi ng\u01b0\u1eddi.<\/p>\n

Doggybone DNA l\u00e0 g\u00ec<\/h2>\n

Th\u00f4ng tin m\u1ee5c ti\u00eau \u0111\u01b0\u1ee3c \u0111\u1eb7t v\u00e0o DNA tuy\u1ebfn t\u00ednh kh\u00e9p k\u00edn l\u00e0m b\u1eb1ng enzyme, kh\u00f4ng c\u1ea7n nu\u00f4i vi khu\u1ea9n. Hai \u0111\u1ea7u k\u00edn t\u1ea1o t\u00ean g\u1ecdi doggybone.<\/p>\n

D\u1ee5ng c\u1ee5 kh\u00f4ng kim \u0111\u01b0a vaccine v\u00e0o c\u01a1; l\u1ecbch \u0111\u0103ng k\u00fd l\u00e0 m\u1ed7i ba tu\u1ea7n trong 24 tu\u1ea7n r\u1ed3i m\u1ed7i s\u00e1u tu\u1ea7n c\u00f9ng pembrolizumab.<\/p>\n

\"H\u00ecnh
H\u00ecnh minh h\u1ecda do ONEPRESS t\u1ea1o: m\u00f4 t\u1ea3 quy tr\u00ecnh vaccine DNA c\u00e1 nh\u00e2n, kh\u00f4ng ph\u1ea3i b\u1ec7nh nh\u00e2n, s\u1ea3n ph\u1ea9m hay ph\u00f2ng th\u00ed nghi\u1ec7m NEOVACC th\u1eadt.<\/figcaption><\/figure>\n

Ai \u0111\u01b0\u1ee3c tham gia<\/h2>\n

Ng\u01b0\u1eddi l\u1edbn c\u00f3 NSCLC ti\u1ebfn tri\u1ec3n ho\u1eb7c t\u00e1i ph\u00e1t, PD-L1 \u00edt nh\u1ea5t 50% v\u00e0 kh\u1ed1i u ch\u01b0a s\u1ea1ch sau anti-PD-1.<\/p>\n

B\u1ec7nh ti\u1ebfn tri\u1ec3n qu\u00e1 nhanh kh\u00f4ng ch\u1edd s\u1ea3n xu\u1ea5t ho\u1eb7c \u0111\u00e3 \u0111\u00e1p \u1ee9ng ho\u00e0n to\u00e0n s\u1ebd b\u1ecb lo\u1ea1i. \u0110\u00e2y ch\u01b0a ph\u1ea3i ch\u0103m s\u00f3c ph\u1ed5 bi\u1ebfn.<\/p>\n

Li\u1ec1u \u0111\u1ea7u ch\u1ee9ng minh g\u00ec<\/h2>\n

N\u00f3 cho th\u1ea5y sinh thi\u1ebft, ch\u1ecdn m\u1ee5c ti\u00eau, s\u1ea3n xu\u1ea5t ri\u00eang v\u00e0 giao thu\u1ed1c c\u00f3 th\u1ec3 ho\u00e0n th\u00e0nh. M\u00e1u v\u00e0 sinh thi\u1ebft l\u1eb7p s\u1ebd theo d\u00f5i mi\u1ec5n d\u1ecbch v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5.<\/p>\n

Ch\u01b0a c\u00f3 k\u1ebft qu\u1ea3 co u, ng\u1eeba t\u00e1i ph\u00e1t hay k\u00e9o d\u00e0i s\u1ed1ng. C\u00e1 nh\u00e2n h\u00f3a kh\u00f4ng t\u1ef1 ch\u1ee9ng minh hi\u1ec7u qu\u1ea3.<\/p>\n

Theo d\u00f5i \u0111i\u1ec1u g\u00ec ti\u1ebfp theo<\/h2>\n

Nghi\u00ean c\u1ee9u s\u1ebd xem t\u1ebf b\u00e0o T c\u00f3 nh\u1eadn \u0111\u00fang m\u1ee5c ti\u00eau ung th\u01b0 hay kh\u00f4ng. \u0110\u0103ng k\u00fd ch\u00ednh th\u1ee9c v\u1eabn \u0111ang di\u1ec5n ra v\u00e0 ch\u01b0a c\u00f3 k\u1ebft qu\u1ea3 c\u00f4ng b\u1ed1.<\/p>\n

An to\u00e0n, th\u1eddi gian s\u1ea3n xu\u1ea5t, s\u1ed1 ng\u01b0\u1eddi th\u1ef1c t\u1ebf v\u00e0 \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch s\u1ebd quy\u1ebft \u0111\u1ecbnh th\u1eed nghi\u1ec7m l\u1edbn h\u01a1n.<\/p>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p ch\u00ednh th\u1ee9c<\/h2>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p: UK Research and Innovation first-patient announcement<\/a><\/p>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p: UK Health Research Authority NEOVACC summary<\/a><\/p>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p: ISRCTN11752949 official trial registration<\/a><\/p>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p: Clatterbridge Cancer Centre trial announcement<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

NEOVACC \u0111\u1ecdc \u0111\u1ed9t bi\u1ebfn kh\u1ed1i u \u0111\u1ec3 t\u1ea1o vaccine DNA ri\u00eang. B\u1ec7nh nh\u00e2n Anh \u0111\u1ea7u ti\u00ean \u0111\u00e3 nh\u1eadn thu\u1ed1c, nh\u01b0ng th\u1eed nghi\u1ec7m \u0111\u1ea7u \u1edf ng\u01b0\u1eddi ch\u1ec9 \u0111\u00e1nh gi\u00e1 an to\u00e0n v\u00e0 mi\u1ec5n d\u1ecbch, ch\u01b0a ch\u1ee9ng minh hi\u1ec7u qu\u1ea3.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-954","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}