{"id":876,"date":"2026-07-27T09:50:00","date_gmt":"2026-07-27T00:50:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-27-who-doxypep-first-guideline-vi\/"},"modified":"2026-07-27T09:50:00","modified_gmt":"2026-07-27T00:50:00","slug":"2026-07-27-who-doxypep-first-guideline-vi","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-27-who-doxypep-first-guideline-vi\/","title":{"rendered":"WHO khuy\u1ebfn ngh\u1ecb doxycycline trong 72 gi\u1edd \u0111\u1ec3 ph\u00f2ng m\u1ed9t s\u1ed1 STI do vi khu\u1ea9n"},"content":{"rendered":"

2026-07-27 09:50 KST<\/strong><\/p>\n

T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi ban h\u00e0nh khuy\u1ebfn ngh\u1ecb to\u00e0n c\u1ea7u \u0111\u1ea7u ti\u00ean v\u1ec1 d\u1ef1 ph\u00f2ng sau ph\u01a1i nhi\u1ec5m b\u1eb1ng doxycycline, DoxyPEP, \u0111\u1ec3 gi\u1ea3m STI do vi khu\u1ea9n.<\/p>\n

B\u00e1c s\u0129 c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc m\u1ed9t li\u1ec1u 200 mg, t\u1ed1t nh\u1ea5t trong 24 gi\u1edd v\u00e0 kh\u00f4ng mu\u1ed9n h\u01a1n 72 gi\u1edd sau quan h\u1ec7 kh\u00f4ng d\u00f9ng bao cao su, cho nam quan h\u1ec7 \u0111\u1ed3ng gi\u1edbi v\u00e0 ph\u1ee5 n\u1eef chuy\u1ec3n gi\u1edbi c\u00f3 nguy c\u01a1 nhi\u1ec5m g\u1ea7n \u0111\u00e2y ho\u1eb7c t\u00e1i di\u1ec5n.<\/p>\n

Hi\u1ec7u qu\u1ea3 ph\u00f2ng ng\u1eeba trong th\u1eed nghi\u1ec7m<\/h2>\n

B\u1eb1ng ch\u1ee9ng th\u1eed nghi\u1ec7m ng\u1eabu nhi\u00ean WHO t\u1ed5ng h\u1ee3p cho th\u1ea5y gi\u1ea3m 80% giang mai, 85% chlamydia v\u00e0 48% l\u1eadu. Trong th\u1eed nghi\u1ec7m M\u1ef9 501 ng\u01b0\u1eddi, STI do vi khu\u1ea9n theo qu\u00fd gi\u1ea3m kho\u1ea3ng hai ph\u1ea7n ba. Hi\u1ec7u qu\u1ea3 v\u1edbi l\u1eadu thay \u0111\u1ed5i theo kh\u00e1ng tetracycline \u0111\u1ecba ph\u01b0\u01a1ng.<\/p>\n

Khuy\u1ebfn ngh\u1ecb \u00e1p d\u1ee5ng cho ai<\/h2>\n

WHO \u01b0u ti\u00ean ng\u01b0\u1eddi c\u00f3 STI trong 12 th\u00e1ng tr\u01b0\u1edbc ho\u1eb7c thu\u1ed9c m\u1ea1ng l\u01b0\u1edbi c\u00f3 t\u1ef7 l\u1ec7 cao. K\u00ea \u0111\u01a1n ph\u1ea3i n\u1eb1m trong d\u1ecbch v\u1ee5 s\u1ee9c kh\u1ecfe t\u00ecnh d\u1ee5c g\u1ed3m x\u00e9t nghi\u1ec7m \u0111\u1ecbnh k\u1ef3, d\u1ef1 ph\u00f2ng ho\u1eb7c \u0111i\u1ec1u tr\u1ecb HIV, ti\u00eam ch\u1ee7ng, bao cao su v\u00e0 t\u01b0 v\u1ea5n.<\/p>\n

\"H\u00ecnh
H\u00ecnh minh h\u1ecda do ONEPRESS t\u1ea1o: gi\u1ea3i th\u00edch th\u1eddi \u0111i\u1ec3m DoxyPEP v\u00e0 gi\u00e1m s\u00e1t kh\u00e1ng thu\u1ed1c, kh\u00f4ng ph\u1ea3i qu\u1ea3ng c\u00e1o hay h\u01b0\u1edbng d\u1eabn li\u1ec1u d\u00f9ng.<\/figcaption><\/figure>\n

Nh\u1eefng nh\u00f3m c\u00f2n thi\u1ebfu b\u1eb1ng ch\u1ee9ng<\/h2>\n

Th\u1eed nghi\u1ec7m 449 ph\u1ee5 n\u1eef h\u1ee3p gi\u1edbi \u1edf Kenya kh\u00f4ng cho th\u1ea5y gi\u1ea3m c\u00f3 \u00fd ngh\u0129a. Tu\u00e2n th\u1ee7 th\u1ea5p v\u00e0 m\u1eabu l\u1eadu kh\u00e1ng tetracycline cao. Ch\u01b0a \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng m\u1edf r\u1ed9ng cho ph\u1ee5 n\u1eef h\u1ee3p gi\u1edbi, v\u1ecb th\u00e0nh ni\u00ean hay nh\u00f3m kh\u00e1c; WHO c\u0169ng kh\u00f4ng khuy\u1ebfn ngh\u1ecb DoxyPrEP h\u1eb1ng ng\u00e0y.<\/p>\n

V\u00ec sao kh\u00f4ng t\u1ef1 \u00fd d\u00f9ng<\/h2>\n

Doxycycline l\u00e0 kh\u00e1ng sinh k\u00ea \u0111\u01a1n, c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n n\u00f4n, k\u00edch \u1ee9ng th\u1ef1c qu\u1ea3n v\u00e0 nh\u1ea1y n\u1eafng. V\u1ea5n \u0111\u1ec1 l\u1edbn h\u01a1n l\u00e0 kh\u00e1ng thu\u1ed1c. \u1ea2nh h\u01b0\u1edfng d\u00e0i h\u1ea1n l\u00ean h\u1ec7 vi sinh ru\u1ed9t v\u00e0 vi khu\u1ea9n kh\u00e1c v\u1eabn ch\u01b0a ch\u1eafc ch\u1eafn.<\/p>\n

\u0110i\u1ec1u ng\u01b0\u1eddi d\u00f9ng c\u1ea7n ki\u1ec3m tra<\/h2>\n

\u0110\u00e2y kh\u00f4ng ph\u1ea3i h\u01b0\u1edbng d\u1eabn t\u1ef1 mua v\u00e0 u\u1ed1ng kh\u00e1ng sinh. C\u1ea7n trao \u0111\u1ed5i v\u1edbi b\u00e1c s\u0129 ho\u1eb7c ch\u01b0\u01a1ng tr\u00ecnh s\u1ee9c kh\u1ecfe t\u00ecnh d\u1ee5c ch\u00ednh th\u1ee9c v\u1ec1 \u0111i\u1ec1u ki\u1ec7n, x\u00e9t nghi\u1ec7m, t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u00e0 gi\u00e1m s\u00e1t kh\u00e1ng thu\u1ed1c \u0111\u1ecba ph\u01b0\u01a1ng.<\/p>\n

Ngu\u1ed3n s\u01a1 c\u1ea5p ch\u00ednh th\u1ee9c<\/h2>\n

WHO: full DoxyPEP guideline, evidence tables and monitoring conditions<\/a><\/p>\n

WHO: first global DoxyPEP recommendation announcement<\/a><\/p>\n

NEJM: randomized DoxyPEP trial in 501 MSM and transgender women<\/a><\/p>\n

NEJM: randomized trial in 449 cisgender women in Kenya<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Khuy\u1ebfn ngh\u1ecb DoxyPEP to\u00e0n c\u1ea7u \u0111\u1ea7u ti\u00ean c\u1ee7a WHO cho ph\u00e9p b\u00e1c s\u0129 c\u00e2n nh\u1eafc m\u1ed9t li\u1ec1u 200 mg, t\u1ed1t nh\u1ea5t trong 24 gi\u1edd v\u00e0 kh\u00f4ng qu\u00e1 72 gi\u1edd sau quan h\u1ec7 kh\u00f4ng d\u00f9ng bao cao su, cho m\u1ed9t s\u1ed1 nam quan h\u1ec7 \u0111\u1ed3ng gi\u1edbi v\u00e0 ph\u1ee5 n\u1eef chuy\u1ec3n gi\u1edbi nguy c\u01a1 cao. \u0110\u00e2y kh\u00f4ng ph\u1ea3i t\u1ef1 d\u00f9ng thu\u1ed1c hay khuy\u1ebfn ngh\u1ecb cho to\u00e0n d\u00e2n.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-876","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/876","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=876"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}