{"id":839,"date":"2026-07-26T08:40:00","date_gmt":"2026-07-25T23:40:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-26-scn2a-personalized-aso-ja\/"},"modified":"2026-07-26T08:48:52","modified_gmt":"2026-07-25T23:48:52","slug":"2026-07-26-scn2a-personalized-aso-ja","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-07-26-scn2a-personalized-aso-ja\/","title":{"rendered":"2\u4eba\u306e\u305f\u3081\u306b\u5225\u3005\u306b\u4f5c\u3063\u305f\u6cbb\u7642\u3001\u767a\u4f5c\u304c26%\u30fb90%\u6e1b\u5c11"},"content":{"rendered":"<p><strong>2026-07-26 08:40 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class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/onepress.co.kr\/wp-content\/uploads\/2026\/07\/scn2a-personalized-aso-ja.png\" alt=\"\u5909\u7570SCN2A\u30b3\u30d4\u30fc\u7531\u6765RNA\u3092\u500b\u5225ASO\u304c\u6291\u3048\u3001\u6b63\u5e38\u30b3\u30d4\u30fc\u3092\u4fdd\u3064\u4ed5\u7d44\u307f\u3092\u793a\u3059\u5236\u4f5c\u79d1\u5b66\u753b\u50cf\" loading=\"lazy\" \/><figcaption class=\"op-briefing-image-caption\">\u5236\u4f5c\u753b\u50cf\uff1aONEPRESS\u304c\u500b\u5225ASO\u306b\u3088\u308b\u5909\u7570\u907a\u4f1d\u5b50\u30b3\u30d4\u30fc\u306e\u9078\u629e\u7684\u6291\u5236\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306b\u69cb\u6210\u3057\u305f\u3002\u5b9f\u5728\u60a3\u8005\u3084\u6cbb\u7642\u5834\u9762\u3067\u306f\u306a\u3044\u3002<\/figcaption><\/figure>\n<h2>\u5e0c\u5c11\u75be\u60a3\u306e\u958b\u767a\u5358\u4f4d\u304c\u500b\u4eba\u306b\u306a\u3063\u305f<\/h2>\n<p>\u8a3a\u65ad\u540d\u5168\u4f53\u306b\u4e00\u3064\u306e\u85ac\u3092\u4f7f\u3046\u306e\u3067\u306f\u306a\u304f\u3001\u4e00\u4eba\u306e\u30b2\u30ce\u30e0\u306b\u5408\u308f\u305b\u3066\u88fd\u54c1\u3092\u8a2d\u8a08\u3057\u8a66\u3059\u3002\u5927\u898f\u6a21\u8a66\u9a13\u304c\u96e3\u3057\u3044\u6975\u3081\u3066\u5e0c\u5c11\u306a\u5909\u7570\u306b\u3082\u9053\u3092\u4f5c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n<p>\u5225\u306e\u4e73\u5150\u30b3\u30db\u30fc\u30c8\u3067\u306f\u7d0416%\u304c\u3053\u306e\u8a2d\u8a08\u306b\u9069\u3057\u305f\u8fd1\u508d\u30de\u30fc\u30ab\u30fc\u3092\u6301\u3063\u3066\u3044\u305f\u3002\u62e1\u5927\u306e\u53ef\u80fd\u6027\u3092\u793a\u3059\u304c\u3001\u5168SCN2A\u60a3\u8005\u306b\u4f7f\u3048\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u306a\u3044\u3002<\/p>\n<h2>\u4e00\u822c\u5316\u3067\u304d\u306a\u3044\u7406\u7531<\/h2>\n<p>\u5404\u60a3\u8005\u306f\u6cbb\u7642\u524d\u306e\u81ea\u5206\u3068\u6bd4\u8f03\u3055\u308c\u3001\u7121\u4f5c\u70ba\u5316\u3082\u5bfe\u7167\u7fa4\u3082\u306a\u3044\u3002\u767a\u9054\u5909\u5316\u304b\u3089\u767a\u4f5c\u6e1b\u5c11\u3001\u85ac\u306e\u8abf\u6574\u3001\u6210\u9577\u306e\u5f71\u97ff\u3092\u5b8c\u5168\u306b\u306f\u5206\u3051\u3089\u308c\u305a\u3001\u9577\u671f\u5b89\u5168\u6027\u3082\u8ffd\u52a0\u8ffd\u8de1\u304c\u5fc5\u8981\u3060\u3002<\/p>\n<p>\u500b\u5225\u6cbb\u7642\u304c\u6e2c\u5b9a\u53ef\u80fd\u306a\u81e8\u5e8a\u5909\u5316\u3092\u751f\u3080\u3053\u3068\u306f\u793a\u3057\u305f\u304c\u3001\u5e83\u304f\u5229\u7528\u3067\u304d\u308b\u6a19\u6e96\u6cbb\u7642\u304c\u78ba\u7acb\u3057\u305f\u308f\u3051\u3067\u306f\u306a\u3044\u3002<\/p>\n<h2>\u6b21\u306e\u78ba\u8a8d\u70b9<\/h2>\n<p>\u52b9\u679c\u304c\u7d9a\u304f\u304b\u3001\u9ac4\u8154\u5185\u53cd\u5fa9\u6295\u4e0e\u304c\u9577\u671f\u306b\u5b89\u5168\u304b\u3001\u540c\u3058\u8a2d\u8a08\u6cd5\u3092\u4ed6\u306e\u907a\u4f1d\u6027\u75be\u60a3\u3078\u3069\u308c\u307b\u3069\u901f\u304f\u5e83\u3052\u3089\u308c\u308b\u304b\u304c\u6b21\u306e\u5224\u65ad\u6750\u6599\u306b\u306a\u308b\u3002<\/p>\n<h2>\u516c\u5f0f\u4e00\u6b21\u8cc7\u6599<\/h2>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42481851\/\" target=\"_blank\" rel=\"noopener noreferrer\">Nature Medicine \/ PubMed original study<\/a><\/p>\n<p><a href=\"https:\/\/radygenomics.org\/2026\/personalized-gene-therapy-helps-teen-with-rare-form-of-severe-epilepsy-walk-independently\/\" target=\"_blank\" rel=\"noopener noreferrer\">Rady Children&#8217;s Institute for Genomic Medicine study release<\/a><\/p>\n<p><a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06314490\" target=\"_blank\" rel=\"noopener noreferrer\">ClinicalTrials.gov NCT06314490<\/a><\/p>\n<p><a href=\"https:\/\/www.cirm.ca.gov\/clinical-trial\/personalized-antisense-oligonucleotide-therapy-for-rare-pediatric-genetic-disease-scn2a\/\" target=\"_blank\" rel=\"noopener noreferrer\">California Institute for Regenerative Medicine trial record<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SCN2A\u95a2\u9023\u306e\u91cd\u3044\u767a\u9054\u6027\u3066\u3093\u304b\u3093\u3092\u6301\u30642\u4eba\u306b\u3001\u305d\u308c\u305e\u308c\u306e\u5909\u7570\u30b3\u30d4\u30fc\u3092\u72d9\u3046ASO\u3092\u6295\u4e0e\u3057\u305f\u3068\u3053\u308d\u30012\u5e74\u9593\u3067\u767a\u4f5c\u983b\u5ea6\u304c26%\u306890%\u6e1b\u3063\u305f\u3002\u305f\u3060\u3057\u5bfe\u7167\u7fa4\u306e\u306a\u30442\u4ef6\u306en-of-1\u8a66\u9a13\u3067\u3042\u308b\u3002<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-839","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/839","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=839"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}