{"id":2383,"date":"2026-09-30T01:28:00","date_gmt":"2026-09-29T16:28:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-30-thermostable-mrna-lnp-vi\/"},"modified":"2026-09-30T01:28:00","modified_gmt":"2026-09-29T16:28:00","slug":"2026-09-30-thermostable-mrna-lnp-vi","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-30-thermostable-mrna-lnp-vi\/","title":{"rendered":"H\u1ea1t mang mRNA ch\u1ecbu \u0111\u01b0\u1ee3c m\u1ed9t n\u0103m \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, nh\u01b0ng m\u1edbi th\u1eed tr\u00ean chu\u1ed9t"},"content":{"rendered":"

2026-09-30 01:28 KST<\/strong><\/p>\n

Nh\u00f3m MIT t\u00ecm ra c\u00f4ng th\u1ee9c b\u1ea3o qu\u1ea3n h\u1ea1t nano lipid mRNA kh\u00f4 t\u1edbi m\u1ed9t n\u0103m \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng v\u00e0 hai th\u00e1ng \u1edf 37\u00b0C.<\/p>\n

K\u1ebft qu\u1ea3 n\u00e0y kh\u00f4ng x\u00e1c l\u1eadp h\u1ea1n d\u00f9ng cho vaccine \u0111\u00e3 ph\u00ea duy\u1ec7t. C\u00f4ng th\u1ee9c mang kh\u00e1ng nguy\u00ean COVID-19 \u0111\u01b0\u1ee3c ki\u1ec3m tra tr\u00ean chu\u1ed9t, kh\u00f4ng ph\u1ea3i ng\u01b0\u1eddi.<\/p>\n

H\u1ecd \u0111\u00e3 thay \u0111\u1ed5i g\u00ec<\/h2>\n

Nh\u00f3m \u0111i\u1ec1u ch\u1ec9nh h\u1ed7n h\u1ee3p v\u00e0 t\u1ef7 l\u1ec7 \u0111\u01b0\u1eddng, mu\u1ed1i v\u00e0 polymer quanh h\u1ea1t lipid ch\u1ee9 kh\u00f4ng \u0111\u1ed5i mRNA. H\u1ecd s\u00e0ng l\u1ecdc kho\u1ea3ng 50 t\u00e1 d\u01b0\u1ee3c \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn, ch\u1ecdn n\u0103m ch\u1ea5t v\u00e0 d\u00f9ng thu\u1eadt to\u00e1n ti\u1ebft ki\u1ec7m d\u1eef li\u1ec7u \u0111\u1ec3 quy\u1ebft \u0111\u1ecbnh c\u00e1c t\u1ed5 h\u1ee3p th\u1eed ti\u1ebfp theo.<\/p>\n

C\u00e1c m\u1ed1c th\u1eddi gian c\u00f3 ngh\u0129a g\u00ec<\/h2>\n

Sau khi s\u1ea5y ch\u00e2n kh\u00f4ng v\u00e0 l\u01b0u tr\u1eef, h\u1ea1t t\u1ea1o \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch \u1edf chu\u1ed9t t\u01b0\u01a1ng \u0111\u01b0\u01a1ng c\u00f4ng th\u1ee9c \u0111\u1ed1i ch\u1ee9ng ki\u1ec3u Moderna. \u0110i\u1ec1u \u0111\u00f3 ch\u01b0a ch\u1ee9ng minh hi\u1ec7u qu\u1ea3 v\u1edbi m\u1ecdi kh\u00e1ng nguy\u00ean, \u1edf quy m\u00f4 s\u1ea3n xu\u1ea5t hay trong \u0111i\u1ec1u ki\u1ec7n v\u1eadn chuy\u1ec3n th\u1ef1c t\u1ebf.<\/p>\n

\"H\u1ea1t
\u0110\u00e2y l\u00e0 h\u00ecnh \u1ea3nh t\u1ea1o b\u1eb1ng AI \u0111\u1ec3 gi\u1ea3i th\u00edch ch\u1ee7 \u0111\u1ec1, kh\u00f4ng ph\u1ea3i \u1ea3nh s\u1ef1 ki\u1ec7n, quan s\u00e1t hay hi\u1ec7n tr\u01b0\u1eddng th\u1ef1c t\u1ebf.<\/figcaption><\/figure>\n

V\u00ec sao \u0111\u00e1ng ch\u00fa \u00fd<\/h2>\n

RNA d\u1ec5 ph\u00e2n h\u1ee7y n\u00ean nhi\u1ec1u s\u1ea3n ph\u1ea9m c\u1ea7n chu\u1ed7i l\u1ea1nh. N\u1ebfu \u0111\u1ed9 b\u1ec1n nhi\u1ec7t \u1edf tr\u1ea1ng th\u00e1i kh\u00f4 \u0111\u01b0\u1ee3c l\u1eb7p l\u1ea1i, c\u00f4ng ngh\u1ec7 c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 ph\u00e2n ph\u1ed1i v\u00e0 mi\u1ebfng d\u00e1n vi kim h\u00f2a tan, nh\u01b0ng chi ph\u00ed, s\u1ea3n xu\u1ea5t v\u00e0 ph\u00ea duy\u1ec7t v\u1eabn l\u00e0 r\u00e0o c\u1ea3n ri\u00eang.<\/p>\n

C\u1ea7n ki\u1ec3m tra ti\u1ebfp g\u00ec<\/h2>\n

C\u1ea7n nghi\u00ean c\u1ee9u an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 \u1edf ng\u01b0\u1eddi, th\u1eed nhi\u1ec1u lo\u1ea1i RNA, m\u1edf r\u1ed9ng s\u1ea3n xu\u1ea5t v\u00e0 \u0111o \u0111\u1eb7c t\u00ednh h\u1ea1t sau b\u1ea3o qu\u1ea3n d\u00e0i ng\u00e0y. B\u00e0i b\u00e1o c\u0169ng c\u00f4ng b\u1ed1 quan h\u1ec7 b\u1eb1ng s\u00e1ng ch\u1ebf, t\u01b0 v\u1ea5n v\u00e0 doanh nghi\u1ec7p, n\u00ean vi\u1ec7c t\u00e1i l\u1eadp \u0111\u1ed9c l\u1eadp r\u1ea5t quan tr\u1ecdng.<\/p>\n

Ngu\u1ed3n g\u1ed1c v\u00e0 ki\u1ec3m ch\u1ee9ng \u0111\u1ed9c l\u1eadp<\/h2>\n

Ngu\u1ed3n g\u1ed1c: Nature Biotechnology \uc6d0 \ub17c\ubb38<\/a><\/p>\n

Gi\u1ea3i th\u00edch c\u1ee7a t\u1ed5 ch\u1ee9c: MIT News \uc5f0\uad6c \uc124\uba85<\/a><\/p>\n

Ki\u1ec3m ch\u1ee9ng \u0111\u1ed9c l\u1eadp: Nature \ub17c\ubb38 \uc11c\uc9c0\u00b7\ub3d9\ub8cc\uc2ec\uc0ac \uc815\ubcf4<\/a><\/p>\n

\u0110\u1ecdc b\u1eb1ng ng\u00f4n ng\u1eef kh\u00e1c<\/h2>\n

\ud55c\uad6d\uc5b4<\/a> \u00b7 English<\/a> \u00b7 Espa\u00f1ol<\/a> \u00b7 \u65e5\u672c\u8a9e<\/a> \u00b7 Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

M\u1ed9t h\u1ed7n h\u1ee3p t\u00e1 d\u01b0\u1ee3c do AI h\u1ed7 tr\u1ee3 l\u1ef1a ch\u1ecdn gi\u1eef h\u1ea1t nano lipid mRNA kh\u00f4 ho\u1ea1t \u0111\u1ed9ng m\u1ed9t n\u0103m \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng v\u00e0 hai th\u00e1ng \u1edf 37\u00b0C. \u0110\u00e2y ch\u01b0a ph\u1ea3i h\u1ea1n d\u00f9ng c\u1ee7a vaccine \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p; \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch ch\u1ec9 \u0111\u01b0\u1ee3c th\u1eed tr\u00ean chu\u1ed9t.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-2383","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/2383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=2383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}