{"id":2288,"date":"2026-09-26T01:12:00","date_gmt":"2026-09-25T16:12:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-26-chromosome-fragile-sites-vi\/"},"modified":"2026-09-26T01:12:00","modified_gmt":"2026-09-25T16:12:00","slug":"2026-09-26-chromosome-fragile-sites-vi","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-26-chromosome-fragile-sites-vi\/","title":{"rendered":"L\u1eadp b\u1ea3n \u0111\u1ed3 t\u1eebng t\u1ebf b\u00e0o cho th\u1ea5y nhi\u1ec1u nh\u00f3m \u201c\u0111i\u1ec3m d\u1ec5 g\u00e3y\u201d tr\u00ean nhi\u1ec5m s\u1eafc th\u1ec3"},"content":{"rendered":"

2026-09-26 01:12 KST<\/strong><\/p>\n

Nh\u00f3m l\u00e0m gi\u00e1n \u0111o\u1ea1n nh\u1eb9 sao ch\u00e9p DNA b\u1eb1ng aphidicolin r\u1ed3i ph\u00e2n t\u00edch v\u1ecb tr\u00ed g\u00e3y v\u00e0 th\u1eddi \u0111i\u1ec3m sao ch\u00e9p \u1edf 480 t\u1ebf b\u00e0o \u0111\u01a1n.<\/p>\n

H\u1ecd th\u1ea5y c\u1ea3 \u0111i\u1ec3m d\u1ec5 g\u00e3y \u0111\u00e3 bi\u1ebft l\u1eabn s\u1ef1 ki\u1ec7n hi\u1ebfm b\u1ecb che trong trung b\u00ecnh qu\u1ea7n th\u1ec3, r\u1ed3i ph\u00e2n nh\u00f3m theo v\u1ecb tr\u00ed v\u00e0 ki\u1ec3u sao ch\u00e9p.<\/p>\n

V\u00ec sao trung b\u00ecnh b\u1ecf s\u00f3t<\/h2>\n

Tr\u1ed9n nhi\u1ec1u t\u1ebf b\u00e0o l\u00e0m n\u1ed5i c\u00e1c v\u1ecb tr\u00ed l\u1eb7p l\u1ea1i. B\u1ea3n \u0111\u1ed3 t\u1eebng t\u1ebf b\u00e0o gi\u1eef c\u1ea3 s\u1ef1 ki\u1ec7n \u1edf m\u1ed9t ho\u1eb7c hai t\u1ebf b\u00e0o v\u00e0 n\u1ed1i v\u1edbi tr\u1ea1ng th\u00e1i sao ch\u00e9p xung quanh.<\/p>\n

Kh\u00f4ng ch\u1ec9 m\u1ed9t nguy\u00ean nh\u00e2n<\/h2>\n

M\u1ed9t s\u1ed1 tr\u00f9ng gen l\u1edbn sao ch\u00e9p mu\u1ed9n; nh\u00f3m kh\u00e1c li\u00ean quan \u00edt \u0111i\u1ec3m kh\u1edfi \u0111\u1ea7u hay v\u00f9ng ranh gi\u1edbi. Ch\u1ec9 \u201csao ch\u00e9p mu\u1ed9n\u201d kh\u00f4ng \u0111\u1ee7 gi\u1ea3i th\u00edch.<\/p>\n

\"L\u1eadp
\u0110\u00e2y l\u00e0 h\u00ecnh \u1ea3nh t\u1ea1o b\u1eb1ng AI \u0111\u1ec3 gi\u1ea3i th\u00edch ch\u1ee7 \u0111\u1ec1, kh\u00f4ng ph\u1ea3i \u1ea3nh s\u1ef1 ki\u1ec7n, quan s\u00e1t hay hi\u1ec7n tr\u01b0\u1eddng th\u1ef1c t\u1ebf.<\/figcaption><\/figure>\n

Gi\u1edbi h\u1ea1n v\u1edbi ung th\u01b0<\/h2>\n

Stress sao ch\u00e9p quan tr\u1ecdng trong ung th\u01b0 nh\u01b0ng nghi\u00ean c\u1ee9u kh\u00f4ng \u0111o kh\u1ed1i u hay k\u1ebft qu\u1ea3 b\u1ec7nh nh\u00e2n. Lo\u1ea1i t\u1ebf b\u00e0o v\u00e0 \u0111i\u1ec1u ki\u1ec7n thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u1ed5i b\u1ea3n \u0111\u1ed3.<\/p>\n

Ti\u1ebfp theo<\/h2>\n

C\u1ea7n t\u00e1i l\u1eadp \u1edf t\u1ebf b\u00e0o kh\u00e1c v\u00e0 stress t\u1ef1 nhi\u00ean. So v\u1edbi t\u00e1i s\u1eafp x\u1ebfp trong kh\u1ed1i u s\u1ebd cho bi\u1ebft \u0111\u1ee9t g\u00e3y hi\u1ebfm n\u00e0o t\u1ed3n t\u1ea1i trong b\u1ec7nh.<\/p>\n

Ngu\u1ed3n g\u1ed1c v\u00e0 ki\u1ec3m ch\u1ee9ng \u0111\u1ed9c l\u1eadp<\/h2>\n

Ngu\u1ed3n g\u1ed1c: Nature Communications paper<\/a><\/p>\n

Gi\u1ea3i th\u00edch c\u1ee7a t\u1ed5 ch\u1ee9c: RIKEN research release<\/a><\/p>\n

Ki\u1ec3m ch\u1ee9ng \u0111\u1ed9c l\u1eadp: JST science release index<\/a><\/p>\n

\u0110\u1ecdc b\u1eb1ng ng\u00f4n ng\u1eef kh\u00e1c<\/h2>\n

\ud55c\uad6d\uc5b4<\/a> \u00b7 English<\/a> \u00b7 Espa\u00f1ol<\/a> \u00b7 \u65e5\u672c\u8a9e<\/a> \u00b7 Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ph\u00e2n t\u00edch to\u00e0n h\u1ec7 gen t\u1eebng t\u1ebf b\u00e0o b\u1eaft \u0111\u01b0\u1ee3c \u0111\u1ee9t g\u00e3y hi\u1ebfm v\u00e0 cho th\u1ea5y c\u00e1c nh\u00f3m \u0111i\u1ec3m d\u1ec5 g\u00e3y c\u00f3 th\u1eddi \u0111i\u1ec3m sao ch\u00e9p v\u00e0 nguy\u00ean nh\u00e2n kh\u00e1c nhau. Th\u00ed nghi\u1ec7m d\u00f9ng t\u1ebf b\u00e0o \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa nu\u00f4i c\u1ea5y v\u00e0 thu\u1ed1c, kh\u00f4ng ph\u1ea3i x\u00e9t nghi\u1ec7m d\u1ef1 \u0111o\u00e1n ung th\u01b0 c\u00e1 nh\u00e2n.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-2288","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/2288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=2288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}