{"id":2251,"date":"2026-09-25T01:11:00","date_gmt":"2026-09-24T16:11:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-es\/"},"modified":"2026-09-25T01:11:00","modified_gmt":"2026-09-24T16:11:00","slug":"2026-09-25-psychad-brain-atlas-es","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-es\/","title":{"rendered":"Un atlas prefrontal re\u00fane 6,32 millones de n\u00facleos de 1.494 donantes"},"content":{"rendered":"<p><strong>2026-09-25 01:11 KST<\/strong><\/p>\n<p>Incluye edades de 0 a 108 a\u00f1os y Alzheimer, Parkinson, esquizofrenia, trastorno bipolar y donantes sin problema neurol\u00f3gico.<\/p>\n<p>Los cambios ligados a desarrollo neuronal y sinapsis coincidieron especialmente entre demencias y Parkinson.<\/p>\n<h2>Por qu\u00e9 n\u00facleo por n\u00facleo<\/h2>\n<p>Promediar tejido oculta c\u00e9lulas raras y diferencias entre tipos. El RNA de n\u00facleo separa d\u00f3nde cambia cada gen.<\/p>\n<h2>6,32 millones no son personas<\/h2>\n<p>Son n\u00facleos tras control de calidad; hubo 1.494 donantes \u00fanicos.<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/onepress.co.kr\/wp-content\/uploads\/2026\/09\/psychad-brain-atlas-es.png\" alt=\"Un atlas prefrontal re\u00fane 6,32 millones de n\u00facleos de 1.494 donantes\" loading=\"lazy\" \/><figcaption class=\"op-briefing-image-caption\">Esta imagen generada por IA explica el tema; no es una fotograf\u00eda de un evento, observaci\u00f3n o lugar real.<\/figcaption><\/figure>\n<h2>Qu\u00e9 permite<\/h2>\n<p>Explora cambios comunes y espec\u00edficos y riesgo gen\u00e9tico por ascendencia. Una asociaci\u00f3n no prueba causa ni tratamiento.<\/p>\n<h2>L\u00edmites<\/h2>\n<p>Estado post mortem, diagn\u00f3stico, medicaci\u00f3n y causa de muerte pueden influir. Faltan otras regiones, poblaciones y pruebas funcionales.<\/p>\n<h2>Fuente primaria y comprobaciones independientes<\/h2>\n<p>Fuente primaria: <a href=\"https:\/\/doi.org\/10.1038\/s41586-025-09573-z\" target=\"_blank\" rel=\"noopener noreferrer\">Nature cross-disorder paper<\/a><\/p>\n<p>Explicaci\u00f3n institucional: <a href=\"https:\/\/www.natureasia.com\/en\/info\/press-releases\/detail\/9445\" target=\"_blank\" rel=\"noopener noreferrer\">Nature Portfolio programme summary<\/a><\/p>\n<p>Comprobaci\u00f3n independiente: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12144096\/\" target=\"_blank\" rel=\"noopener noreferrer\">NIH\/PMC PsychAD cohort<\/a><\/p>\n<h2>Leer en otros idiomas<\/h2>\n<p><a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-ko\/\">\ud55c\uad6d\uc5b4<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-en\/\">English<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-es\/\">Espa\u00f1ol<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-ja\/\">\u65e5\u672c\u8a9e<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-25-psychad-brain-atlas-vi\/\">Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>PsychAD analiz\u00f3 6.320.459 n\u00facleos con control de calidad de corteza prefrontal post mortem de 1.494 personas con varios trastornos. No es una prueba diagn\u00f3stica ni demuestra una causa \u00fanica.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-2251","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/2251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=2251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}