{"id":2168,"date":"2026-09-22T01:07:00","date_gmt":"2026-09-21T16:07:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-22-rotifer-transgenerational-dna-repair-en\/"},"modified":"2026-09-22T01:07:00","modified_gmt":"2026-09-21T16:07:00","slug":"2026-09-22-rotifer-transgenerational-dna-repair-en","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-22-rotifer-transgenerational-dna-repair-en\/","title":{"rendered":"Rotifers repaired shattered chromosomes across multiple generations"},"content":{"rendered":"

2026-09-22 01:07 KST<\/strong><\/p>\n

Researchers found that chromosome fragments not fully repaired at once could pass to later generations, where missing regions were restored using an intact homologous chromosome as a template.<\/p>\n

They call the process BIHER, expanding the simple idea that DNA repair must finish within one individual and one generation.<\/p>\n

Why is it surprising?<\/h2>\n

These rotifers withstand ionising-radiation doses more than 100 times those lethal to humans. Such exposure can fragment chromosomes into tens or hundreds of pieces.<\/p>\n

How did repair continue?<\/h2>\n

Some damaged fragments were retained and inherited. In descendants, an intact homologous chromosome served as the template for progressively rebuilding missing DNA regions.<\/p>\n

\"Rotifers
This AI-generated image explains the topic; it is not a photograph of an actual event, observation or field site.<\/figcaption><\/figure>\n

What does it explain?<\/h2>\n

The flexible process helps explain rotifer resistance to radiation and desiccation and shows how a genome can still be transmitted after severe damage.<\/p>\n

Limits and next work<\/h2>\n

The finding comes from one unusual asexual lineage. It does not directly translate to cancer treatment or human genome repair; other species and molecular accuracy need independent testing.<\/p>\n

Primary source and independent checks<\/h2>\n

Science Advances \uc6d0 \ub17c\ubb38<\/a><\/p>\n

FNRS \uc5f0\uad6c \uc124\uba85<\/a><\/p>\n

Read in other languages<\/h2>\n

\ud55c\uad6d\uc5b4<\/a> \u00b7 English<\/a> \u00b7 Espa\u00f1ol<\/a> \u00b7 \u65e5\u672c\u8a9e<\/a> \u00b7 Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

In the asexual rotifer Adineta vaga, fragments of heavily damaged chromosomes persisted into descendants and were gradually repaired. This mechanism was observed in this animal under experimental conditions; it is not a human DNA therapy.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-2168","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/2168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=2168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}