{"id":2047,"date":"2026-09-14T01:10:00","date_gmt":"2026-09-13T16:10:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-en\/"},"modified":"2026-09-14T01:10:00","modified_gmt":"2026-09-13T16:10:00","slug":"2026-09-14-bone-marrow-plasma-cell-chip-en","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-en\/","title":{"rendered":"Human marrow-on-a-chip exposed how antibody cells move and settle"},"content":{"rendered":"<p><strong>2026-09-14 01:10 KST<\/strong><\/p>\n<p>Human B cells were matured into antibody-secreting plasma cells and moved into a chip with two marrow-like niches.<\/p>\n<p>The platform can test questions and candidates but cannot establish clinical efficacy or long-term safety.<\/p>\n<h2>System<\/h2>\n<p>An inactivated-flu organoid stage was linked to microfluidic perivascular and endosteal-like niches.<\/p>\n<h2>Observation<\/h2>\n<p>Hair-width channels enabled high-resolution imaging of movement, stopping and survival signals.<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/onepress.co.kr\/wp-content\/uploads\/2026\/09\/bone-marrow-plasma-cell-chip-en.png\" alt=\"Human marrow-on-a-chip exposed how antibody cells move and settle\" loading=\"lazy\" \/><figcaption class=\"op-briefing-image-caption\">This AI-generated image explains the topic; it is not a photograph of the actual site, experiment, animal or fossil.<\/figcaption><\/figure>\n<h2>Importance<\/h2>\n<p>Long-lived plasma cells sustain antibodies; dysregulation can contribute to allergy, autoimmunity and blood cancer.<\/p>\n<h2>Limits<\/h2>\n<p>Donor cells, artificial gels and growth factors simplify a body with circulation, nerves, hormones and many cell types.<\/p>\n<h2>Next<\/h2>\n<p>Different donors and diseases must reproduce results, followed by comparison with animals and patient samples.<\/p>\n<h2>Primary source and independent checks<\/h2>\n<p><a href=\"https:\/\/api.crossref.org\/works\/10.1126\/sciadv.adz3976\" target=\"_blank\" rel=\"noopener noreferrer\">Science Advances \uc6d0 \ub17c\ubb38 \uc11c\uc9c0<\/a><\/p>\n<p><a href=\"https:\/\/news.research.gatech.edu\/2026\/09\/11\/window-hidden-world-immunity-inside-human-bone-marrow\" target=\"_blank\" rel=\"noopener noreferrer\">\uc870\uc9c0\uc544\uacf5\ub300 \uae30\uad00 \uc124\uba85<\/a><\/p>\n<h2>Read in other languages<\/h2>\n<p><a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-ko\/\">\ud55c\uad6d\uc5b4<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-en\/\">English<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-es\/\">Espa\u00f1ol<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-ja\/\">\u65e5\u672c\u8a9e<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-14-bone-marrow-plasma-cell-chip-vi\/\">Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A linked lymphoid organoid and vascular marrow chip let researchers observe plasma-cell migration and survival. It is not a complete body model or a new treatment.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-2047","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/2047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=2047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}