{"id":1990,"date":"2026-09-12T13:30:00","date_gmt":"2026-09-12T04:30:00","guid":{"rendered":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-vi\/"},"modified":"2026-09-12T13:30:00","modified_gmt":"2026-09-12T04:30:00","slug":"2026-09-12-esophagus-treatment-selection-vi","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-vi\/","title":{"rendered":"V\u00e0i tu\u1ea7n \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u0111\u1ed5i cu\u1ed9c c\u1ea1nh tranh c\u1ee7a t\u1ebf b\u00e0o \u0111\u1ed9t bi\u1ebfn trong th\u1ef1c qu\u1ea3n b\u00ecnh th\u01b0\u1eddng"},"content":{"rendered":"<p><strong>2026-09-12 13:30 KST<\/strong><\/p>\n<p>Ni\u00eam m\u1ea1c th\u1ef1c qu\u1ea3n b\u00ecnh th\u01b0\u1eddng l\u1ea5y khi ph\u1eabu thu\u1eadt cho th\u1ea5y h\u00f3a tr\u1ecb v\u00e0 h\u00f3a-x\u1ea1 tr\u1ecb \u01b0u ti\u00ean c\u00e1c qu\u1ea7n th\u1ec3 \u0111\u1ed9t bi\u1ebfn kh\u00e1c nhau ch\u1ec9 sau 5\u20138 tu\u1ea7n.<\/p>\n<p>K\u1ebft qu\u1ea3 ch\u00ednh l\u00e0 ch\u1ecdn clone c\u00f3 s\u1eb5n, kh\u00f4ng ch\u1ee9ng minh t\u1ea1o m\u1ecdi \u0111\u1ed9t bi\u1ebfn. Ph\u1ea7n l\u1edbn \u0111\u1ed9t bi\u1ebfn soma kh\u00f4ng th\u00e0nh ung th\u01b0 v\u00e0 nghi\u00ean c\u1ee9u kh\u00f4ng d\u1ef1 b\u00e1o t\u00e1i ph\u00e1t c\u00e1 nh\u00e2n.<\/p>\n<h2>So s\u00e1nh<\/h2>\n<p>70 ng\u01b0\u1eddi g\u1ed3m kh\u00f4ng ti\u1ec1n tr\u1ecb 21, ECX 17, EOX 14, FLOT 7 v\u00e0 CROSS 11; kh\u00f4ng ph\u1ea3i m\u1eabu gh\u00e9p tr\u01b0\u1edbc-sau.<\/p>\n<h2>Thay \u0111\u1ed5i<\/h2>\n<p>Clone TP53 v\u00e0 PPM1D t\u0103ng \u1edf CROSS; RAC1, NFE2L2 v\u00e0 MTOR \u0111\u01b0\u1ee3c ch\u1ecdn \u1edf FLOT.<\/p>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"https:\/\/onepress.co.kr\/wp-content\/uploads\/2026\/09\/esophagus-treatment-selection-vi.png\" alt=\"V\u00e0i tu\u1ea7n \u0111i\u1ec1u tr\u1ecb ung th\u01b0 \u0111\u1ed5i cu\u1ed9c c\u1ea1nh tranh c\u1ee7a t\u1ebf b\u00e0o \u0111\u1ed9t bi\u1ebfn trong th\u1ef1c qu\u1ea3n b\u00ecnh th\u01b0\u1eddng\" loading=\"lazy\" \/><figcaption class=\"op-briefing-image-caption\">\u0110\u00e2y l\u00e0 h\u00ecnh \u1ea3nh t\u1ea1o b\u1eb1ng AI \u0111\u1ec3 gi\u1ea3i th\u00edch ch\u1ee7 \u0111\u1ec1, kh\u00f4ng ph\u1ea3i \u1ea3nh ch\u1ee5p \u0111\u1ecba \u0111i\u1ec3m, th\u00ed nghi\u1ec7m, \u0111\u1ed9ng v\u1eadt hay h\u00f3a th\u1ea1ch th\u1ef1c t\u1ebf.<\/figcaption><\/figure>\n<h2>\u0110\u1ed9t bi\u1ebfn m\u1edbi<\/h2>\n<p>Kh\u00f4ng th\u1ea5y ch\u1eef k\u00fd \u0111\u1ed9t bi\u1ebfn h\u00f3a tr\u1ecb r\u00f5 d\u00f9 \u0111\u1ed9 th\u00edch nghi thay \u0111\u1ed5i, n\u00ean ph\u1ea3i t\u00e1ch t\u1ea1o m\u1edbi v\u00e0 ch\u1ecdn l\u1ecdc.<\/p>\n<h2>Gi\u1edbi h\u1ea1n<\/h2>\n<p>N\u0103m nh\u00f3m nh\u1ecf, nh\u1eafm 324 gene v\u00e0 ch\u1ec9 gi\u1ea3i tr\u00ecnh t\u1ef1 m\u00f4 sau \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Ti\u1ebfp theo<\/h2>\n<p>Th\u1eed nghi\u1ec7m \u0111ang l\u1ea5y t\u1ebf b\u00e0o m\u00e1, m\u00e1u v\u00e0 n\u01b0\u1edbc ti\u1ec3u tr\u01b0\u1edbc-sau \u0111i\u1ec1u tr\u1ecb ung th\u01b0 kh\u00e1c. Kh\u00f4ng ph\u1ea3i l\u00fd do ng\u1eebng thu\u1ed1c.<\/p>\n<h2>Ngu\u1ed3n g\u1ed1c v\u00e0 ki\u1ec3m ch\u1ee9ng \u0111\u1ed9c l\u1eadp<\/h2>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41588-026-02738-0\" target=\"_blank\" rel=\"noopener noreferrer\">Nature Genetics \uc6d0 \ub17c\ubb38<\/a><\/p>\n<p><a href=\"https:\/\/www.sanger.ac.uk\/news_item\/chemotherapy-alters-darwinian-battleground-in-our-bodies\/\" target=\"_blank\" rel=\"noopener noreferrer\">Wellcome Sanger Institute \uc5f0\uad6c \ubc1c\ud45c<\/a><\/p>\n<p><a href=\"https:\/\/ega-archive.org\/dacs\/EGAC00001000000\" target=\"_blank\" rel=\"noopener noreferrer\">EGA \uc5f0\uad6c \ub370\uc774\ud130 \uc124\uba85<\/a><\/p>\n<h2>\u0110\u1ecdc b\u1eb1ng ng\u00f4n ng\u1eef kh\u00e1c<\/h2>\n<p><a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-ko\/\">\ud55c\uad6d\uc5b4<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-en\/\">English<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-es\/\">Espa\u00f1ol<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-ja\/\">\u65e5\u672c\u8a9e<\/a> \u00b7 <a href=\"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-12-esophagus-treatment-selection-vi\/\">Ti\u1ebfng Vi\u1ec7t<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u00f4 b\u00ecnh th\u01b0\u1eddng c\u1ee7a 70 b\u1ec7nh nh\u00e2n cho th\u1ea5y m\u1ed7i ph\u00e1c \u0111\u1ed3 \u01b0u ti\u00ean clone c\u00f3 s\u1eb5n kh\u00e1c nhau. Kh\u00f4ng c\u00f3 ngh\u0129a \u0111i\u1ec1u tr\u1ecb t\u1ea1o m\u1ecdi \u0111\u1ed9t bi\u1ebfn hay ch\u00fang ch\u1eafc ch\u1eafn th\u00e0nh ung th\u01b0.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-1990","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/1990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=1990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}