{"id":1824,"date":"2026-09-06T06:00:00","date_gmt":"2026-09-05T21:00:00","guid":{"rendered":"https:\/\/onepress.co.kr\/?post_type=briefing&p=1824"},"modified":"2026-09-06T06:14:32","modified_gmt":"2026-09-05T21:14:32","slug":"2026-09-06-pig-kidney-271-day-bridge-en","status":"publish","type":"briefing","link":"https:\/\/onepress.co.kr\/index.php\/briefing\/2026-09-06-pig-kidney-271-day-bridge-en\/","title":{"rendered":"Pig kidney bridged 271 dialysis-free days before a human transplant"},"content":{"rendered":"

2026-09-06 05:58 KST<\/strong><\/p>\n

A patient with end-stage kidney disease lived for 271 days without dialysis using a gene-edited pig kidney, then successfully transitioned to a donated human kidney. Reported in The Lancet on September 3, it is the longest dialysis-free survival with a pig kidney in a living person and the first documented bridge to a human organ.<\/p>\n

This does not show that pig kidneys solve the organ shortage or last for life. It was one patient under an FDA expanded-access protocol, and the xenograft developed microvascular injury and inflammation after immunosuppression was reduced during an infection.<\/p>\n

What happened to the patient?<\/h2>\n

Tim Andrews, 66 at xenotransplant, had received hemodialysis for two years. The kidney worked immediately, an early T-cell rejection episode was treated, and no pig pathogen transmission was detected.<\/p>\n

Why did the graft fail?<\/h2>\n

After about six months, immunosuppression was reduced during infection. Microvascular injury and inflammation progressed to failure, identifying problems future trials must address.<\/p>\n

\"Pig
This AI-generated image explains the topic; it is not a photograph of the actual event, observation, or experiment.<\/figcaption><\/figure>\n

What happened next?<\/h2>\n

Eighty-two days after removal, he received a deceased-donor human kidney with immediate function. Follow-up found no evidence of sensitization, but longer monitoring is needed.<\/p>\n

Why call it a bridge?<\/h2>\n

The organ temporarily replaced dialysis while a human kidney was awaited; it was not permanent therapy. Surgery, infection and immunosuppression risks remain substantial.<\/p>\n

What must be checked next?<\/h2>\n

More patients, longer follow-up, infection surveillance and immune effects on later human transplantation are needed. One case cannot provide an average success rate.<\/p>\n

Primary sources and independent checks<\/h2>\n

Lancet \uc6d0 \ub17c\ubb38<\/a><\/p>\n

Mass General Brigham \uc5f0\uad6c \ubc1c\ud45c<\/a><\/p>\n

Euronews \ub3c5\ub9bd \ud655\uc778<\/a><\/p>\n

FDA \uc774\uc885\uc774\uc2dd \uc784\uc0c1 \uc548\ub0b4<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

A gene-edited pig kidney worked for 271 days before one patient received a human kidney. This is a single early case, and the xenograft eventually failed.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":[],"class_list":["post-1824","briefing","type-briefing","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing\/1824","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/briefing"}],"about":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/types\/briefing"}],"wp:attachment":[{"href":"https:\/\/onepress.co.kr\/index.php\/wp-json\/wp\/v2\/media?parent=1824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}